Jessica L. Petersen

Jessica L. Petersen

Associate Professor
Animal Functional Genomics


  • University of California Davis, 2009 Ph.D. in Genetics
  • Western Illinois University, 2003 M.S. in Biology
  • Nebraska Wesleyan University, 2000 B.S. in Biology

Professional Experience

  • Associate Professor – University of Nebraska Lincoln, Dept of Animal Science - Animal Functional Genomics (July 2020 – current)
  • Assistant Professor – University of Nebraska Lincoln, Department of Animal Science (Jan 2014 – June 2020)
  • Courtesy Assistant Professor – University of Nebraska-Lincoln, Biological Sciences (July 2016-present)
  • Postdoctoral Researcher – University of Minnesota College of Veterinary Medicine, Equine Genetics and Genomics (2009-Dec 2013)
  • Graduate Student Researcher – Genomic Variation Laboratory, University of California-Davis (2004-2009)

Peer-Reviewed Publications (ǂ-mentored student/post-doc, ɫ -lab manager)

  • Gurgul A, Szmatoła T, Ocłoń E, Jasielczuk I, Semik-Gurgul E, Finno CJ, Petersen JL, Bellone RR, Hales EN, Ząbek T, Arent Z, Kotula-Balak M, Bugno-Poniewierska M. Another lesson from unmapped reads – in depth analysis of RNA-Seq reads from various horse tissues. Journal of Applied Genetics. In Press. doi:10.1007/213353-022-00705-z.
  • Sieck RLǂ, Treffer LKǂ, Fuller AM ɫ, PointeViana M, Khalimonchuk O, Schmidt TB, Yates DT, Petersen JL. Beta-adrenergic agonists alter oxidative phosphorylation in primary myoblasts. Journal of Animal Science. In Press.
  • Wilson CS, Petersen JL, Blackburn HD, Lewis RM. Assessing population structure and genetic diversity in the US Suffolk sheep to define a framework for genomic selection. Journal of Heredity. In Press. doi:10.1093/jhered/esac026.
  • Posont RJ, Most MS, Cadaret CN, Marks-Nelson E, Beede KA, Limesand SW, Schmidt TB, Petersen JL, Yates DT. Primary myoblasts from intrauterine growth-restricted fetal sheep exhibit intrinsic dysfunction of proliferation and differentiation that coincides with enrichment of inflammatory cytokine signaling pathways. Journal of Animal Science. In Press.
  • Valberg SJ, Henry ML, Herrick KL, Velez-Irizarry, Finno CJ, Petersen JL. Absence of myofibrillar myopathy in Quarter Horses with a histopathologic diagnosis of type 2 polysaccharide storage myopathy and lack of association with commercial genetic tests. Equine Veterinary Journal. In Press. doi:10.1111/evj.13574.
  • Wang Z, Chivu AG, Choate LA, Rice EJ, Miller DC, Chu T, Chou S-P, Kingsley NB, Petersen JL, Finno CJ, Bellone RR, Antczak DF, Lis JT, Danko CG. Interdependence between histone marks and steps in Pol II transcription. Nature Genetics. In Press.
  • Reith RRǂ, Sieck RLǂ, Grijalva PC, Swanson R, Fuller AM ɫ, Diaz DE, Schmidt TB, Yates DT, Petersen JL. 2022. Transcriptome analyses indicate that heat stress-induced inflammation in white adipose tissue and oxidative stress in skeletal muscle is partially moderated by zilpaterol supplementation in beef cattle. Journal of Animal Science. Journal of Animal Science. 100(3):skac109.
  • Bailey E, Petersen JL, Kalbflesich T. Invited Review: Genetics of Thoroughbred racehorse performance. 2022 Annual Review of Animal Biosciences. 10:131-150.
  • Horvath S, Haghani A, Peng S, Hales EN, Zoller JA, Raj K, Larison B, Robeck TR, Petersen JL, Bellone RR, Finno CJ. 2022. DNA methylation aging and transcriptomic studies in horses. Nature Communications. Nature Communications. 13:40.
  • Cadaret CT, Posont RJ, Swanson RM, Beard JK, Gibbs RL, Barnes TL, Marks-Nelson ES, Petersen JL, Yates DT. 2021. Intermittent maternofetal oxygenation during late gestation improved birthweight, neonatal growth, body symmetry, and muscle metabolism in intrauterine growth-restricted lambs. Journal of Animal Science.
  • Peng S, Petersen JL, Bellone RR, Kalbfleisch T, Kingsley NB, Barber AM, Cappelletti E, Giulotto E, Finno CJ. 2021. Decoding the Equine Genome: Lessons from ENCODE. Genes. 12(11): 1707.
  • Barnes TBǂ, Burrack RMǂ, Schmidt TB, Petersen JL, Yates DT. 2021. Sustained heat stress elevated corneal and body surface temperatures and altered circulating leukocytes and metabolic indicators in wether lambs supplemented with ractopamine or zilpaterol. Journal of Animal Science. 99:skab236. doi:10.1093/jas/skab236.
  • Peng S, Bellone RR, Petersen JL, Kalbfleisch TS, Finno CJ. Successful ATAC-seq from snap-frozen equine tissues. 2021. Frontiers in Genetics. 12:641788. doi:10.3389/fgene.2021.641788.
  • Herrera NJ, Bland NA, Ribeiro FA, Henriott ML, Hofferber EM, Meier J, Petersen JL, Iverson NM, Calkins CR. 2021. Oxidative stress and postmortem meat quality in crossbred lambs. Journal of Animal Science. 99:skab156. doi:10.1093/jas/skab156.
  • Posont RJ, Cadaret CN, Beard JK, Swanson RM, Gibbs RM, Marks-Nelson ES, Petersen JL, Yates DT. 2021. Maternofetal inflammation induced for two weeks in late gestation reduced birthweight and impaired neonatal growth and skeletal muscle glucose metabolism in lambs. Journal of Animal Science. 99:skab102. doi:10.1093/jas/skab102
  • Kingsley NB, Hamilton N, Lindgren G, Orlando L, Bailey E, Brooks SB, McCue M, Kalbfleisch TS, MacLeod JN, Petersen JL, Finno CJ, Bellone RR. 2021. Adopt-a-tissue initiative advances efforts to identify tissue-specific histone marks in the mare. Frontiers in Genetics. 12:390. doi:10.3389/fgene.2021.649959.
  • Donnelly CG, Bellone RR, Hales E, Nguyen A, Katzman S, Dujovne G, Knickelbein K, Avila F, Kablfleisch T, Guiulotto E, Kingsley NB, Tanaka J, Esedaile E, Peng S, Dahlgren A, Fuller A, Mienaltowski M, Raudsepp T, Affolter V, Petersen JL, Finno CJ. 2021. Generation of a Biobank From Two Adult Thoroughbred Stallions for the Functional Annotation of Animal Genomes Initiative. Frontiers in Genetics. 12:301. doi:10.3389/fgene.2021.650305.
  • Yousefi Mashouf N, Mehrabani Yeganeh H, Nejati Javaremi A, Bailey E, Petersen JL. 2021. Genomic comparisons of Persian Kurdish, Persian Arabian, and American Thoroughbred horse populations. PLoS One. 16(2):e0247123. doi:10.1371/journal.pone.0247123.
  • Valberg SJ, Finno CJ, Henry M, Schott M, Velez-Irizarry D, Peng S, McKenzie E, Petersen JL. 2021. Commercial genetic testing for type 2 polysaccharide storage myopathy and myofibrillar myopathy does not correspond to a histopathologic diagnosis. Equine Veterinary Journal. 53: 690-700.
  • Kalbfleisch T, Petersen JL, Tait Jr. RG, Qiu J, Basnayake V, Hackett P, Heaton MP. 2020. Using triallelic SNPs for determining parentage in North American yak (Bos grunniens) and estimating cattle (B. taurus) introgression. F1000. doi:10.12688/f1000research.25803.2
  • Sieck RLǂ, Fuller AM ɫ, Bedwell PS, Ward JA, Sanders SK, Xiang S-H, Peng S, Petersen JL, Steffen DJ. 2020. Mandibulofacial dysostosis attributed to a recessive mutation of CYP26C1 in Hereford cattle. Genes. 11:1246. doi:10.3390/genes11111246
  • Dahlgren A, Scott E, Mansour T, Hales E, Ross P, Kalbfleisch TS, MacLeod JN, Petersen JL, Bellone RR, Finno CJ. 2020. Comparison of Poly-A+ Selection and rRNA Depletion in Detection of lncRNA in Two Equine Tissues Using RNA-seq. ncRNA. 6(3):32.
  • Petersen JL, Coleman SJ. 2020. Invited Review: Next-generation sequencing in equine genomics. Veterinary Clinics: Equine Practice. 36:195-209.
  • Williams Z, Velez-Irizarry D, Petersen JL, Ochala J, Finno CJ, Valberg SJ. Candidate gene expression and coding sequence variants in Warmblood horses with myofibrillar myopathy. Equine Veterinary Journal. In Press.
  • Swanson RM, Tait Jr RG, Galles RM, Duffy EM, Schmidt TB, Petersen JL, Yates DT. Heat stress-induced deficits in growth, metabolic efficiency, and cardiovascular function coincided with chronic systemic inflammation and hypercatecholaminemia in ractopamine-supplemented feedlot lambs. Journal of Animal Science. 98:skaa168.
  • Rice ESǂ, Koren S, Rhie A, Heaton MP, Kalbfleisch TS, Hardy T, Hackett PH, Bickhart DM, Rosen BD, Vander Ley B, Maurer NW, Green RE, Phillippy AM, Petersen JL, Smith TPL. 2020. Chromosome-length haplotigs for yak and cattle from trio binning assembly of an F1 hybrid. Gigascience. 9:giaa029.
  • Helms A, Thompson RE, Lawton S, Petersen JL, Watson A, Sula M-J, Steffen DJ, Whitlock BK. 2020. Uterine torsion dystocia complicated by Perosomus elumbis in an Angus calf associated with a consanguineous mating. Case Reports in Veterinary Medicine. 2020:6543037.
  • Nilson SMǂ, Workman AM, Sjeklocha D, Brodersen B, Grotelueschen DM, Petersen JL. 2020. Upregulation of the type I interferon pathway in feedlot cattle persistently infected with bovine viral diarrhea virus. Virus Research. 278:197862.
  • Petersen JL, Kalbfleisch TS, Parris Mǂ, Tietze SM ɫ, Cruickshank J. 2020. MC1R and KIT haplotypes associate with coat color in North American yak (Bos grunniens). Journal of Heredity. 111:169-181.
  • Kingsley NB, Kern C, Creppe C, Hales EN, Zhou H, Kalbfleisch TS, MacLeod JN, Petersen JL, Finno CJ, Bellone RR. 2020. Functionally annotating regulatory elements in the equine genome using histone mark ChIP-Seq. Genes. 11:3.
  • Burrack RMǂ, Duffy EMǂ, Yates DT, Schmidt TB, Petersen JL. 2020. Whole blood transcriptome analysis in feedlot cattle after 35-days of supplementation with a β1-adrenergic agonist. Journal of Applied Genetics. 61:117-121.
  • Cadaret CN, Merrick EM, Barnes TLǂ, Beede KA, Posont RJ, Petersen JL, Yates DT. 2019. Sustained maternal inflammation during the early third trimester yields intrauterine growth restriction, impaired skeletal muscle glucose metabolism, and diminished β cell function in fetal sheep. Journal of Animal Science. 97:4822-4833.
  • Raudsepp T, Finno CJ, Bellone RR, Petersen JL. 2019. Ten years of the horse reference genome: insights into equine biology, domestication and population dynamics in the post-genome era. Animal Genetics. 50:569-597.
  • Barnes TBǂ, Cadaret C, Beede K, Schmidt TB, Petersen JL*, Yates DT*. 2019. Hypertrophic muscle growth and metabolic efficiency were impaired by chronic heat stress, improved by zilpaterol supplementation, and not affected by ractopamine supplementation in feedlot lambs. Journal of Animal Science. 97:4101-4113. doi:10/1093/jas/skz271. *authors contributed equally
  • Wijesena HR, Rohrer GA, Nonneman DJ, Keel BN, Petersen JL, Kachman SD, Ciobanu DC. 2019. Evaluation of genotype quality parameters for SowPro90, a noval genotyping array for swine. Journal of Animal Science. 97:3262-3273.
  • Petersen JL, Lewis RM, Embertson RM, Valberg SJ, Holcombe SJ. 2019. Heritability of ≥ 360° large colon volvulus in Thoroughbred broodmares. Veterinary Record. 185:269. doi:10.1136/vr.105323.
  • Tozaki T, Kikuchi M, Kakoi H, Hirota K, Nagata S, Yamashita D, Ohnuma T, Takasu M, Kobayashi I, Hobo S, Manglai D, Petersen JL. 2019. Genetic diversity and relationships among native Japanese horse breeds, the Japanese Thoroughbred, and horses outside of Japan using genome-wide SNP data. Animal Genetics. 50:449-459.
  • Beede KA, Limesand SW, Petersen JL, Yates DT. 2019. Real supermodels wear wool: summarizing the impact of the pregnant sheep as an animal model for adaptive fetal programming. Animal Frontiers. 9:34-43.
  • Petersen JL, Tietze SM ɫ, Burrack RMǂ, Steffen DJ. 2019. Identification of a novel, dominant germ-line mutation causative of osteogenesis imperfecta in Red Angus cattle. Mammalian Genome. doi:10.1007/s00335-019-09794-4.
  • Valberg SJ, Soave K, Williams ZJ, Perumbakkam S, Schott M, Finno CJ, Petersen JL, Fenger C, Autry JM, Thomas DD. 2019. Coding sequences of sarcoplasmic reticulum calcium ATPase regulatory peptides and expression of calcium regulatory genes in recurrent exertional rhabdomyolysis. Journal of Veterinary Internal Medicine. 33(2):933-941. doi:10.1111/jvim.15424.
  • Kalbfleisch TS, Rice ES, DePriest Jr MS, Walenz BP, Hestand MS, Vermeesch JR, O’Connell BL, Fiddes IT, Vershinina AO, Petersen JL, Finno JC, Bellone RR, McCue ME, Brooks SA, Bailey E, Orlando L, Green RE, Miller DC, Antczak DF, MacLeod JN. 2018. Improved reference genome for the domestic horse increases assembly contiguity and composition. Communications Biology 1:197. doi: 10.1038/s42003-018-0199-z.
  • Burns EN, Bordbari M, Mienaltowski MJ, Affolter VK, Barro MV, Gianino F, Gianino G, Giulotto E, Kalbfleisch TS, Katzman SA, Lassaline M, Leeb T, Mack M, Müller EJ, MacLeod JN, Ming-Whitfield B, Alanis CR, Raudsepp T, Scott E, Vig S, Zhou H, Petersen JL, Bellone RR, Finno CJ. 2018. Generation of an equine functional annotation of animal genomes biobank. Animal Genetics. 49(6):564-570. doi: 10.1111/age.12717.
  • Yates DT, Petersen JL, Schmidt TB, Cadaret CN, Barnes TBǂ, Posont RJ, Beede KA. 2018. Fetal origins of impaired muscle growth and metabolic dysfunction: lessons from the heat-stressed pregnant ewe. Journal of Animal Science. 96:2987-3002. doi: 10.1093/jas/sky164.
  • Bellone RR, Liu J, Petersen JL, Mack M, Singer-Berk M, Drögemüller C, Malvick J, Wallner B, Brem G, Penedo MCT, Lassaline M. 2017. A missense mutation in damage specific DNA binding protein 2 is a genetic risk factor for limbal squamous cell carcinoma in horses. International Journal of Cancer. 141:342-353.
  • Tuggle CK, Giuffra E, White SN, Clarke L, Zhou H, Ross PJ, Acloque H, Reecy JM, Archibald A, Bellone RR, Biochard M, Chamberlain A, Cheng H, Crooijmans RPMA, Delany ME, Finno CJ, Groenen MAM, Hayes B, Lunney JK, Petersen JL, Plastow GS, Schmidt CJ, Soung J, Watson M. 2016. GO-FAANG meeting: a gathering on functional annotation of animal genomes. Animal Genetics. 47:528-533.
  • Trenhaile MD, Petersen JL, Kachman SD, Johnson RK, Ciobanu DC. Long-term selection for litter size in swine results in shifts in allelic frequency in regions involved in reproductive processes. 2016. Animal Genetics. 47:534-542.
  • Workman A, Heaton MP, Harhay GP, Smith T, Grotelueschen DM, Sjeklocha D, Brodersen B, Petersen JL, Chitko-McKown CG. 2016. Resolving Bovine viral diarrhea virus subtypes from persistently infected U.S. beef calves with complete genome sequence. Journal of Veterinary Diagnostic Investigation. 28:519-528. *Awarded best JVDI Full Manuscript of the year
  • Petersen JL, Mickelson JR, Valberg SJ, McCue ME. 2015. Genome-wide SNP data shows little differentiation between the Appaloosa and other American stock horse breeds. Animal Genetics. 46:585-586.
  • Morota G, Peñagaricano F, Petersen JL, Ciobanu DC, Tsuyuzaki K, Nikaido I. 2015. An application of MeSH enrichment analysis in livestock. Animal Genetics. 46:381-387.
Photo of Jessica Petersen
Areas of Expertise
Breeding & Genetics