Dr. Andrea Cupp's Laboratory Publications

Publications Since 2013

  • Abedal-Majed MA, M Abuajamieh, M Al-Qaisi, A Abdelqader, KM Sargent, HH Titi,MA Alnimer, AI Shamoun, and AS Cupp. Sheep with Ovarian Androgen Excess have Increased mRNA Abundance for Steroidogenic Enzymes and Gonadotropin Receptors, Fibrosis and Follicular Arrest. 2023 (accepted in Journal of Animal Science).
  • Monaco, CF, MR. Plewes, E Przygrodzka, JW George,JR. Wood, AS Cupp, JS Davis. Basic fibroblast growth factor (FGF2) induces proliferation and collagen production by fibroblasts derived from the bovine corpus luteum. Biology of Reproduction 2023 (Conditionally accepted with revisions).
  • Abedal-Majed MA, Springman SA, Jafar HD, Bell BE, Kurz SG, Wilson KE, Cupp AS.  Naturally occurring androgen excess cows are present in Dairy and Beef Herds and have similar characteristics to women with PCOS. J Anim Sci. 2022 Jun 1;100(6):skac151. doi: 10.1093/jas/skac151.
  • Rowell JE, Blake JE, Roth KM, Sutton CM, Sachse CC, Cupp AS, Geary TW, Zezeski AL, Alexander BM, Ziegler RL, Shipka MP. J Medroxyprogesterone acetate in reindeer bulls: testes histology, cfos activity in the brain, breeding success and semen quality. J Anim Sci. 2022 Jun 1;100(6):skac106. doi: 10.1093/jas/skac106.
  • Abedal-Majed MA, Springman SA, Sutton CM, Snider AP, Bell BE, Hart M, Kurz SG, Bergman J, Summers AF, McFee RM, Davis JS, Wood JR, Cupp AS. VEGFA165 can rescue excess steroid secretion, inflammatory markers and follicle arrest in the ovarian cortex of high A4 cows. Biol Reprod. 2022 Jan 13;106(1):118-131. doi: 10.1093/biolre/ioab201.
  • Przygrodzka E, Monaco CF, Plewes MR, Li G, Wood JR, Cupp AS, Davis JS. Protein Kinase A and 5' AMP-Activated Protein Kinase Signaling Pathways Exert Opposite Effects on Induction of Autophagy in Luteal Cells. Front Cell Dev Biol. 2021 Nov 8;9:723563. doi: 10.3389/fcell.2021.723563. eCollection 2021. PMID: 34820368.
  • Snider AP, SM Romereim, RM McFee, AF Summers, WE Pohlmeier, SG Kurz, JS Davis, JR Wood, AS Cupp. Transcriptomes of bovine ovarian granulosa cells of control and High A4 cows. Data Brief. 2021 Jun 11;37:107217. doi: 10.1016/j.dib.2021.107217. eCollection 2021 Aug.
  • McFee, RM, SM Romereim, AP Snider, AF Summers, WE Pohlmeier, SG Kurz, JS Davis, JR Wood, AS Cupp.  A High-Androgen Microenvironment Inhibits Granulosa Cell Proliferation and Alters Cell Identity.  Molecular and Cellular Endocrinology 2021 April https://doi.org/10.1016/j.mce.2021.111288
  • Nafziger, SR, SC Tenley, AF. Summers, MA. Abedal-Majed, M Hart, J Bergman, SG Kurz, JS Davis, JR Wood, AS Cupp. Attainment and Maintenance of Pubertal Cyclicity May Predict Reproductive Longevity in Beef Heifers. Biol Reprod. 2021 Mar 11:ioab044. doi: 10.1093/biolre/ioab044.
  • Sutton, C.M., Springman, S.A., Abedal-Majed, M.A., Cupp, A.S. Bovine Ovarian Cortex Tissue Culture. J. Vis. Exp. (167), e61668, doi:10.3791/61668 (2021).
  • Talbott HA, Plewes MR, Krause C, Hou X, Zhang P, Rizzo WB, Wood JR, Cupp AS, Davis JS. Formation and characterization of lipid droplets of the bovine corpus luteum. Sci Rep. 2020 Jul 9;10(1):11287. doi: 10.1038/s41598-020-68091-2. PMID: 32647143.
  • Plewes MR, Krause C, Talbott HA, Przygrodzka E, Wood JR, Cupp AS, Davis JS. Trafficking of cholesterol from lipid droplets to mitochondria in bovine luteal cells: Acute control of progesterone synthesis.  FASEB J. 2020 Aug;34(8):10731-10750. doi: 10.1096/fj.202000671R. Epub 2020 Jul 2.
  • Plewes MR, Hou X, Talbott HA, Zhang P, Wood JR, Cupp AS, Davis JS. Luteinizing hormone regulates the phosphorylation and localization of the mitochondrial effector dynamin-related protein-1 (DRP1) and steroidogenesis in the bovine corpus luteum. FASEB J. 2020 Feb 20. doi: 10.1096/fj.201902958R.
  • Abedal-Majed, MA, SG Kurz; AS Springman, AK. McNeel; HC Freetly, V Largen; M Magamage; KM Sargent; JR Wood, RA Cushman; AS Cupp. Vascular Endothelial Growth Factor A isoforms modulate follicle fate independent of diet through diverse signal transduction pathways. Biol Reprod. 2020 Mar 13;102(3):680-692. doi: 10.1093/biolre/ioz211.
  • Abedel-Majed MA, Romereim SM, Davis JS, Cupp AS. Perturbations in Lineage Specification of Granulosa and Theca Cells May Alter Corpus Luteum Formation and Function. Front Endocrinol (Lausanne). 2019 Nov 29;10:832. doi: 10.3389/fendo.2019.00832. eCollection 2019. Review.
  • Plewes, MR,X Hou,P Zhang, JR Wood, AS Cupp, X Lv, C Wang, and JS Davis. Yes-associated protein (YAP) is required for proliferation and function of bovine granulosa cells. Biol Reprod. 2019 Jul 27. pii: ioz139. doi: 10.1093/biolre/ioz139.
  • Abedal-Majed, MA, AS Cupp. Livestock Animals to Study Infertility in Women. Animal Frontiers 2019 July;9(3):28-33. doi: 10.1093/af/vfz017.
  • Tenley, SC, RS Gomes, SL Rosasco, EJ Northrop, JJ Rich, AK McNeel, AF Summers, JR Miles, CC Chase Jr, CA Lents, GA Perry, JR Wood, AS Cupp, RA Cushman.  Maternal Age Influences the Number of Primordial Follicles in the Ovaries of Yearling Angus Heifers Anim Reprod Sci. 2019 Jan;200:105-112. doi: 10.1016/j.anireprosci.2018.12.004. Epub 2018 Dec 12.
  • Hamernik DL, Cupp AS, Davis JS. Triennial Reproduction Symposium: Looking back and moving forward-how reproductive physiology has evolved. J Anim Sci. 2018 Jun 29;96(7):2949-2951. doi: 10.1093/jas/sky148.
  • McFee, RM, AS Cupp, JR Wood.  Comparison of case-based and hands-on laboratory exercises as group-based learning activities to supplement veterinary physiology course lectures.  Advances in Physiology Education. 2018 Jun 1;42(2):182-191. doi: 10.1152/advan.00084.2017.
  • Romereim SM and AS Cupp. “Vascular Cells” in Testis Biology; Volume 1: Male Reproduction in Encyclopedia of Reproduction, Reference Module in Biomedical Sciences. https://doi.org/10.1016/B978-0-12-801238-3.64560-9. 2018.
  • Wood JR and AS Cupp. "Female Endocrinology-Aromatization" in Ovary Biology: Volume II: Female Reproduction in Encyclopedia of Reproduction, Reference Module in Biomedical Sciences. https://doi.org/10.1016/B978-0-12-801238-3.64642-1. 2018.
  • Talbott HA, Hou X, Qiu F, Zhang P, Guda C, Yu F, Cushman RA, Wood JR, Wang C, Cupp AS, Davis JS.  Transcriptomic and bioinformatics analysis of the early time-course of the response to prostaglandin F2 alpha in the bovine corpus luteum. Data Brief. 2017 Sep 1;14:695-706. doi: 10.1016/j.dib.2017.08.026. eCollection 2017 Oct.PMID: 28932774. Free PMC Article.
  • Talbott H, Hou X, Qiu F, Zhang P, Guda C, Yu F, Cushman RA, Wood JR, Wang C, Cupp AS, Davis JS. Early transcriptome responses of the bovine midcycle corpus luteum to prostaglandin F2α includes cytokine signaling. Mol Cell Endocrinol. 2017 May 23. pii: S0303-7207(17)30287-3. doi: 10.1016/j.mce. 2017.05.018.
  • McNeel, AK, ÉM. Soares, AL Patterson, JL Vallet, EC Wright, EL Larimore, OL  Amundson, JR  Miles, CC  Chase Jr., CA Lents, JR Wood, AS Cupp, GA Perry, RA. Cushman.  Beef heifers with diminished numbers of antral follicles have decreased uterine protein secretion. Anim Reprod Sci. 2017 Jan 12. pii: S0378-4320(16)30618-2. doi: 10.1016/j.anireprosci.2017.01.004.
  • Romereim SM,  AF. Summers, WE. Pohlmeier, P Zhang, X Hou, HA Talbott, RA. Cushman, JR. Wood, JS Davis, AS. Cupp. Data In Brief: Transcriptomes of bovine ovarian follicular and luteal cells. Mol Cell Endocrinol. Epub ahead of Print Dec 15, 2016;  http://dx.doi.org/10.1016/j.dib.2016.11.093.
  • Romereim SM,  AF. Summers, WE. Pohlmeier, P Zhang, X Hou, HA Talbott, RA. Cushman, JR. Wood, JS Davis, AS. Cupp. Gene Expression Profiling of Bovine Ovarian Follicular and Luteal Cells Provides Insight into Cellular Identities and Functions. Epub ahead of print 2016 Dec 10; Molecular and Cellular Endocrinology, Volume 439, 5 January 2017, Pages 379-394. DOI: 10.1016/j.dib.2016.11.093.
  • Romereim, S, AS Cupp.  Book Chapter- Invited:  Mesonephric Cell Migration Into the Gonads is a Process Crucial for Testis Development" in R.P. Piprek (ed.), Molecular Mechanisms of Cell Differentiation in Gonad Development, Results and Problems in Cell Differentiation 58, 2016 DOI 10.1007/978-3-319-31973-5_4.
  • Sutovsky, P, AS Cupp, W Thompson and M Baker. Reproductive Systems Biology Tackles Global Issues of Population Growth, Food Safety and Reproductive Health. Cell and Tissue Research. 2016 Jan;363(1):1-5. doi: 10.1007/s00441-015-2323-4.
  • Sargent, KM,  DT Clopton, N Lu, WE Pohlmeier, and AS Cupp. Invited Review: VEGFA Splicing: Divergent Isoforms Regulate Spermatogonial Stem Cell Maintenance. Cell and Tissue Research; 2016 Jan;363(1):31-45. doi: 10.1007/s00441-015-2297-2 Free PMC Article.
  • Sargent KM, RM McFee, R Spuri-Gomes, and AS Cupp. Invited Review:  Vascular Endothelial Growth Factor A:  Just one of multiple mechanisms for Sex-Specific Vascular Development within the testis? J Endocrinol 2015; 227 (2) R31-R50, doi: 10.1530/JOE-15-0342.  
  • Sargent KM, N Lu, DT Clopton, WE Pohlmeier, V Brauer, N  Ferrara, D Silversides, AS Cupp.  Loss of Vascular Endothelial Growth Factor A (VEGFA) isoforms in Granulosa cells using pDMRT-1 cre reduces female fertility by affecting granulosa cell function to arrest follicular development. PLoS One. 2015 Feb 6;10(2):e0116332. doi: 10.1371/journal.pone.0116332. eCollection 2015.  
  • Cushman RA, RG Tait Jr., AK McNeel, ED Forbes, OL Amundson, CA Lents, AK Lindholm-Perry, GA Perry, JR Wood, AS Cupp, TP Smith, HC Freetly, and GL Bennett. A polymorphism in myostatin influences puberty but not fertility in beef heifers, whereas µ-calpain affects first calf birth weight J Anim Sci. 2015 Jan;93(1):117-26. doi: 10.2527/jas.2014-8505.
  • Summers, AF, WE Pohlmeier, KM Sargent, BD Cole, RJ Vinton, SG Kurz, RM McFee, RA Cushman, AS Cupp*, JR Wood.  Altered theca and cumulus oocyte complex gene expression, follicular arrest and reduced fertility in cows with dominant follicle follicular fluid androgen excess. PLoS One. 2014 Oct 16;9(10):e110683. doi: 10.1371/journal.pone.0110683. eCollection 2014.* corresponding author. Open Access
  • Cupp AS. Sertoli Cell Based Gene Therapy? Biol Reprod. 2014 Aug;91(2):40. doi: 10.1095/biolreprod.114.121996. Epub 2014 Jun 18. No abstract available. PMID:24943042. Free article (Invited Commentary).
  • 6Talbott, H, A Delaney, P Zhang, Y Yu, RA.  Cushman, AS Cupp, X Hou, JS  Davis. Effects of IL8 and Immune Cells on the Regulation of Luteal Progesterone Secretion. Reproduction. 2014 Jul;148(1):21-31. doi: 10.1530/REP-13-0602. Epub 2014 Mar 31.
  • Kurz, SG, KL Dennison, NM Samanas, MP Hickman, TL Walker, AS Cupp and JD. Shull. Ept7 Influences Estrogen Action in the Pituitary Gland and Body Weight of Rats. Mamm Genome. 2014 Jun;25(5-6):244-52. doi: 10.1007/s00335-014-9504-4. Epub 2014 Jan 22. PMID:24448715.
  • Mao, D, H. Xiaoying, H. Talbott, R Cushman, A Cupp, JS Davis. ATF3 Expression in the Corpus Luteum: Possible Role in Luteal Regression. Mol Endocrinol. 2013 Dec;27(12):2066-79. doi: 10.1210/me. 2013-1274. Epub 2013 Nov 6.
  • Lu, N, KM Sargent, DT Clopton, WE Pohlmeier, VM Brauer, RM McFee, JS Weber, N Ferrara, DW Silversides, AS Cupp. Conditional loss of Sertoli and germ cell vascular endothelial growth factor A (VEGFA) isoforms causes alterations in genes regulating spermatogonial stem cell homeostasis in male mice Endocrinology. 2013 Dec;154(12):4790-802. doi: 10.1210/en.2013-1363. Epub 2013 Oct 29. PMCID:PMC3836063.
  • McFee, RM, Bott RC, Lu NX, AS Cupp.  Role of Angiogenesis in development of the ovary. Reprod Fertil Dev. 2013;25(2):333-42. [Epub ahead of print]. PMID:23021322.  Open Access