Andrea Cupp

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Andrea Cupp

Irvin T. and Wanda R. Omtvedt Professor of Animal Science Animal Science University of Nebraska-Lincoln

Contact

Address
ANSC A224i
Lincoln NE 68583-0908
Phone
402-472-6424 On-campus 2-6424
Email
acupp2@unl.edu
Website
Website
Website
Website

Dr. Andrea Cupp joined the Department of Animal Science as an assistant professor in 2000 and has served as a professor and reproductive physiologist since 2011. She was honored with the Irvin T. and Wanda R. Omtvedt Professor of Animal Science endowed professorship in 2015. Dr. Cupp also has a courtesy appointment at the University of Nebraska Medical Center in the Department of OBGYN since 2020. She was named a Distinguished Fellow by the Society of the Study of Reproduction (SSR), one of the highest professional scientific honors awarded for outstanding contributions to the scientific discipline of reproductive biology, in 2024. 

Education

Ph.D., Repro Endo/Animal Science, University of Nebraska-Lincoln, 1994
M.S., Repro Endo/Animal Science, University of Nebraska-Lincoln, 1991
B.S., Animal Science, Virginia Tech, 1988

Teaching

ASCI 442/842:Endocrinology
Summary: Mammalian endocrine glands from the standpoint of their structure, their physiological function in relation to the organism, the chemical nature and mechanisms of action of their secretory products, and the nature of anomalies manifested with their dysfunction.

ASCI 896-003: Independent Study in Animal Science (Grant Writing for the Life Sciences)
Summary: Individual or group projects in research, literature review, or extension of course work under the supervision and evaluation of a departmental faculty member.

Research

Dr. Cupp's research interests include using Animal models- Beef Cattle, and rodents, to understand how ovarian environment affects follicle development and female fertility. Her lab is also interested in how females attain puberty and their reproductive health throughout their lifespan. Finally, her lab is interested in how early development of the female and male gonads may affect lifetime productivity.

Selected Publications

  • Lu, N, KM Sargent, DT Clopton, WE Pohlmeier, VM Brauer, RM McFee, JS Weber, N Ferrara, DW Silversides, AS Cupp. Conditional loss of Sertoli and germ cell vascular endothelial growth factor A (VEGFA) isoforms causes alterations in genes regulating spermatogonial stem cell homeostasis in male mice Endocrinology. 2013 Dec;154(12):4790-802. doi: 10.1210/en.2013-1363. Epub 2013 Oct 29. PMCID:PMC3836063.
  • Summers, AF, WE Pohlmeier, KM Sargent, BD Cole, RJ Vinton, SG Kurz, RM McFee, RA Cushman, AS Cupp*, JR Wood. Altered theca and cumulus oocyte complex gene expression, follicular arrest and reduced fertility in cows with dominant follicle follicular fluid androgen excess. PLoS One. 2014 Oct 16;9(10):e110683. doi: 10.1371/journal.pone.0110683.
  • Romereim SM, AF. Summers, WE. Pohlmeier, P Zhang, X Hou, HA Talbott, RA. Cushman, JR. Wood, JS Davis, AS. Cupp. Gene Expression Profiling of Bovine Ovarian Follicular and Luteal Cells Provides Insight into Cellular Identities and Functions. Epub ahead of print 2016 Dec 10; Molecular and Cellular Endocrinology, Volume 439, 5 January 2017, Pages 379-394. DOI: 10.1016/j.dib.2016.11.093.
  • Nafziger, SR, SC Tenley, AF. Summers, MA. Abedal-Majed, M Hart, J Bergman, SG Kurz, JS Davis, JR Wood, AS Cupp. Attainment and Maintenance of Pubertal Cyclicity May Predict Reproductive Longevity in Beef Heifers. Biol Reprod. 2021 Mar 11:ioab044. doi: 10.1093/biolre/ioab044.
  • Abedal-Majed MA, Springman SA, Sutton CM, Snider AP, Bell BE, Hart M, Kurz SG, Bergman J, Summers AF, McFee RM, Davis JS, Wood JR, Cupp AS. VEGFA165 can rescue excess steroid secretion, inflammatory markers and follicle arrest in the ovarian cortex of high A4 cows. Biol Reprod. 2022 Jan 13;106(1):118-131. doi: 10.1093/biolre/ioab201.
  • Hess MK, A Mersha, SS Ference, SR. Nafziger, JA. Keane, AM. Fuller, SG Kurz, CM. Sutton, ML Spangler, JL. Petersen, AS Cupp. Puberty classifications in beef heifers are moderately to highly heritable and associated with candidate genes related to cyclicity and timing of puberty. In review Frontiers in Genetics, Livestock Genetics; Special Issue on Genetic Regulation of Reproduction traits in Livestock Species, Volume 15 - 2024 | https://doi.org/10.3389/fgene.2024.1405456.